Correlations between BOLD and neurochemical responses measured in the human visual cortex at 7T
نویسندگان
چکیده
Correlations between BOLD and neurochemical responses measured in the human visual cortex at 7T Petr Bednarik, Ivan Tkac, Federico Giove, Dinesh K Deelchand, and Silvia Mangia CMRR Dept. of Radiology, University of Minnesota, Minneapolis, MN, United States, CEITEC Central European Institute of Technology, Masaryk University, Brno, Czech Republic, Magnetic Resonance for Brain Investigation Lab, Enrico Fermi Center, Roma, Italy, Dipartimento di Fisica, Sapienza Università di Roma, Roma, Italy
منابع مشابه
Characterization of the BOLD Hemodynamic Response Function at 7T: towards separation of vasculature and parenchyma
Introduction A limitation of T2weighted BOLD fMRI is the confounding contribution of signal from the larger vasculature. An improved BOLD specificity to parenchyma can be achieved at high field strengths such as 7T due to increased contrast-to-noise ratio, and reduced contribution of intravascular signal as compared to lower field strengths. Moreover, at 7T high spatial and temporal resolution ...
متن کاملCombined fMRI-MRS acquires simultaneous glutamate and BOLD-fMRI signals in the human brain
Combined fMRI-MRS is a novel method to non-invasively investigate functional activation in the human brain using simultaneous acquisition of hemodynamic and neurochemical measures. The aim of the current study was to quantify neural activity using combined fMRI-MRS at 7T. BOLD-fMRI and semi-LASER localization MRS data were acquired from the visual cortex of 13 participants during short blocks (...
متن کاملRepeatability of Detecting Visual Cortex Activity in Functional Magnetic Resonance Imaging
Introduction As functional magnetic resonance imaging (fMRI) is too expensive and time consuming, its frequent implementation is difficult. The aim of this study is to evaluate repeatability of detecting visual cortex activity in fMRI. Materials and Methods In this study, 15 normal volunteers (10 female, 5 male; Mean age±SD: 24.7±3.8 years) attended. Functional magnetic resonance images were ob...
متن کاملAn fMRI study of human visual cortex in response to spatiotemporal properties of visual stimuli
ABSTRACT Background: The brain response to temporal frequencies (TF) has been already reported, but with no study reported for different TF with respect to various spatial frequencies (SF). Materials and Methods: fMRI was performed by 1.5T GE-system in 14 volunteers during checkerboard, with TFs of 4, 6, 8 and 10Hz in low and high SFs of 0.5 and 8cpd. Results: Average percentage BOLD signa...
متن کاملInvestigation of metabolic changes in human visual cortex during neuronal activity using functional Proton Magnetic Resonance Spectroscopy at 7T
Stimulation period Fig.1 A representative 7T proton spectrum from a single subject:(A) averaged spectrum acquired at rest; (B) averaged spectrum acquired during stimulation; (C) difference between (A) and (B). The peaks seen at 2.01, 2.10, 2.35 and 3.03ppm in the difference spectrum are attributed to linewidth changes due to the BOLD effect as well as concentration changes of metabolites. (D) s...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2013